Israeli research shows COVID infection after vaccination can cause long-term symptoms

In a new study in Israel, nearly 3% of medical personnel became infected with COVID19 even after being vaccinated, and 19% of them still had symptoms six weeks later.
Although people never expected the vaccine to be perfect, the study results raise questions about its protective effects and show that even people can experience long-term symptoms such as fatigue, mental confusion, and shortness of breath.
Dr. Ashish Jha, Dean of the Brown University School of Public Health, said he found that people still had symptoms several weeks after becoming ill. Although it is not conclusive, it is concerned.
“In fact, there may be risks here, but we don’t know how big the risks are, how big the problems are,” he said.
Most of the sick people in the study had mild symptoms and no one was hospitalized.
But Jha said that he is worried that young, healthy people will contract so-called progressive infections within a few months of being vaccinated. Scientists predict that the protective effect will diminish over time, and the vaccine is expected to be less effective in the elderly and people with existing health problems. But this is not the person who got sick in this study.
Dr. Monica Gandhi, an infectious disease expert at the University of California, San Francisco, said that she was not surprised that several medical staff were infected after being vaccinated because they often contact patients.
“For me, it makes sense that healthcare workers are particularly vulnerable to breakthrough infections,” he said in an email, “making mitigation procedures (universal masking) more important in medical settings.”
The good news is According to a study published in the New England Journal of Medicine on Wednesday, none of the 39 infected people transmitted the coronavirus to others.
People who are fully vaccinated may be infected with COVID, but experts say they are unlikely to be seriously ill. Cardiologist Dr. Eric Topol, founder and head of the Scripps Research and Translation Institute in California, said that the design of the
coronavirus vaccine has never been perfect to protect people from all infections.
He said that current vaccines are very suitable for preventing serious infections deep in the lungs, but cannot prevent upper respiratory tract infections. He said that what we need is a nasal spray vaccine to prevent the coronavirus epidemic.
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Topol said he wants the federal government to prioritize nasal vaccines and injections. “It will be a perfect combination,” he said.
Some researchers believe that the vaccine will reduce the viral load, and people with a lower viral load are less likely to experience persistent symptoms. Topol said this new study questions this.
“Everything is normal for the vaccinated people, but some people will continue to contract new coronary pneumonia, which is really unfortunate,” he said. The
vaccination rate is slowing down, and COVID19 cases of the highly contagious delta variant are on the rise.
After receiving the PfizerBioNTech vaccine, this study followed approximately 1,500 Israeli medical staff for four months. Anyone who tests positive more than 11 days after the second dose is considered a seminal case.
39 people, 2.6% of the total, were diagnosed with the virus. One is immunosuppression; everyone else is healthy, including nurses, maintenance workers, and some doctors.
37 people for whom data are available were infected by unvaccinated people, usually at home.
Two thirds have mild symptoms; the rest do not.
Six weeks after diagnosis, 19% of people reported that they still had at least one symptom: loss of smell, cough, fatigue, weakness, shortness of breath, or muscle pain. Nine employees (23%) were in poor health and were unable to return to work after the necessary 10 days of isolation. It hasn’t come back after six weeks.
Most people have an alpha variant of the virus, which is more contagious than the original version, but less contagious than the delta variant in most cases in the United States today.
In addition to being more contagious, it is not yet clear whether the delta is more dangerous, Jha said.
Paola Preciado was tested for COVID19 in North Miami, Florida on July 15, 2021.
“The evidence on whether the delta is more toxic is really very complicated. I can point to some studies that think it is research and think it is not. , but neither is particularly true, “he said.
Topol said that the best protection is vaccines and social measures such as the use of masks.
“Don’t do an incremental stress test. Wear a mask,” he said. “With a vaccine, you can be sure, but you can’t be 100% sure.”
Contact Karen Weintraub at kweintraub@usatoday.com
USA Today patient safety and health insurance benefits in part from funding from the Masimo Healthcare Ethics, Innovation and Competition Foundation. The Masimo Foundation does not provide editorial opinions.

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